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ea0041ep299 | Clinical case reports - Pituitary/Adrenal | ECE2016

Initial presentation with diabetes insipidus in langerhans cell histiocytosis, can be marker of multisystemic and progressive involvement

Koca Nizameddin , Emlek Gamze , Sisman Pinar , Gullu Koca Tuba , Sengoren Dikis Ozlem , Oz Gul Ozen , Cander Soner

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder most commonly characterized by osteolytic bone lesions. Central nervous system (CNS) involvement observed at 6% and Diabetes insipidus (DI) one of the important signs of CNS involvement.A 40-years-old woman presented with polyuria, polydipsia and headache. Water deprivation test was compatible with DI. Magnetic resonance imaging (MRI) shows 4×4 mm focal thickening at the distal infun...

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Initial presentation with diabetes insipidus in langerhans cell histiocytosis, can be marker of multisystemic and progressive involvement

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